10.1016/j.jss.2011.06.033 J Surg Res
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The presence of multiple hgp genes may allow for selective expression of the Hgp with greatest affinity for the predominant host haemoglobin-haptoglobin phenotype, or alternatively as a strategy to evade the host immune response mounted against a particular Hgp-expressing population (Langlois and Delanghe, 1996)
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214 Under physiological conditions, increased Ca 2+ levels within mitochondria activate OXPHOS, stimulating ATP synthesis, inducing depolarization of the mitochondrial membrane, enhancing cellular respiration, activating Ca 2+ -dependent mitochondrial enzymes, and subsequently facilitating energy accumulation within mitochondria