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Because semaglutide is a protein-based molecule, if taken as a tablet, it would be broken down by digestive acids before it could reach your bloodstream and do its job

Pergolizzi, The Potential Role of Glucagon-Like Peptide-1 (GLP-1) Agonists for Polycystic Ovary Syndrome

Semaglutide and kidney function: post-hoc analysis of the SUSTAIN 17 randomised controlled trials

Effects on Appetite, Glucose, and Metabolism Beyond glucose lowering, semaglutide acts on the hypothalamus to reduce hunger and increase satiety

Most people reach their target semaglutide dose within 16-20 weeks following the standard titration schedule

If you experience these symptoms, seek medical attention immediately