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There is some evidence in skin science that high levels of glutathione can shift the production of melanin from eumelanin (dark) to pheomelanin (light)

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Given that their high toxicity may provoke serious side effects, researchers are proposing different ways to reduce their toxicity without decreasing their efficacy

Infected tissues exhibited a striking decrease in cornified envelope genes, likely due to the destruction of the cornified epithelium by infection