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Glutathione has also been reported to be a substrate for glutathione peroxidase (GPx) an enzyme which reduces hydrogen peroxide (H 2 O 2 ) in the presence of superoxide dismutase [4]

As such, an effective treatment would be expected to augment striatal synaptic connectivity, protect SN neurons from underlying death inducers, and ideally stimulate the replacement of lost SN neurons from preexisting pools of neural stem cells

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Invest Ophthalmol Vis Sci 53(14):13371337 Quiroz-Mercado H, Boyer DS, Campochiaro PA, Heier JS, Kaiser PK, Kornfield J et al (2018) Randomized, prospective, double-masked, controlled phase 2b trial to evaluate the safety & efficacy of ALG-1001 (Luminate) in diabetic macular edema

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