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Conformational change in the ligand-binding domain has been a basic requirement for the construction of FRET-based nanosensors, and also for translating metabolite binding into a change in FRET 26
The orchestration of mouse locomotor behavior involves various brain regions such as the motor cortex, basal ganglia, thalamus, mesencephalic locomotor region (MLR), brainstem (pons/medulla), and cerebellum 82,83
A study using the Fibromyalgia Impact Questionnaire-Revised reported a negative association between dietary folate intake and symptom burden (r=-0.250
2.3.2 FSP1/CoQ/DHODH pathway Ferroptosis suppressor protein 1 (FSP1) is recruited to the plasma membrane via N-terminal myristoylation, where it functions as an NAD(P)H-dependent oxidoreductase that catalyzes the reduction of coenzyme Q (CoQ) to its ubiquinol form (CoQH2)
Diabetes Metab 47:101279 Vedula S, Krzystolik M (2008) Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration