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The SURMOUNT-1 trial demonstrated significant weight loss, with patients losing approximately 15-21% of their body weight at the 15 mg dose over 72 weeks, depending on the statistical method used

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After incubation with hypo-osmotic swelling solution [HOS, containing 6.75 g/L fructose and 3.67 g/L sodium citrate] at 37C for 1 h, plasma membrane integrity of each group (repeated in triplicated)was analyzed by evaluating the modifications of sperm tail to score swollen sperm according to previous publications (61)

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Research into Extracellular Matrix Dynamics Epithalon has been explored for its possible impact on extracellular matrix (ECM) proteins, such as MMP2, which are associated with tissue remodeling

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No major professional guidelines, including those from the American Psychiatric Association and Academy for Eating Disorders, currently recommend GLP-1/GIP receptor agonists for the treatment of BED outside of research settings

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Visceral fat correlates more strongly with cardiovascular disease risk, type 2 diabetes development, and mortality than subcutaneous fat

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