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Islet amyloid in type 2 human diabetes mellitus and adult diabetic cats contains a novel putative polypeptide hormone

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The relatively short half-life, compared with longer-acting compounds in the broader GH-axis class, is part of why Ipamorelin produces a pulsatile, physiologically patterned GH release rather than a sustained elevation, which is one of the reasons it remains a preferred reference tool for studying pulsatile GH secretion patterns

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J Am Acad Dermatol 83 (3): 860-869, 2020

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