The company recently announced positive results from a Phase 3 study conducted in China for oral KAI-7535: after 50 weeks of treatment, subjects experienced an average weight reduction of up to 11.1%, while patients with type 2 diabetes also showed significant decreases in blood glucose levels
It is also produced in the brain, where its receptors are concentrated in regions that govern reward, motivation, and impulse control the very circuits that are hijacked by addiction
Soluble fibre, found in foods like oats, barley, and fruits, is particularly effective in stimulating GLP-1 release
Potential Side Effects and Considerations As with any treatment, PT-141 may have side effects, including nausea, flushing, or mild headaches
Some studies have shown a reduction of the insulin dose and in hypoglycaemic episodes
56% also covered for weight loss Among those that cover GLP-1s, 77% follow their PBMs authorization criteria when the medications are prescribed to manage diabetes