The TKT gene is located on chromosome 3p21.1 and is composed of 15 exons that generate three alternatively spliced mRNAs that collectively encode two distinct protein isoforms
The LD liquid diet is composed of 45% fat-derived calories, 15% protein-derived calories and 40% calories comprised varying concentrations of carbohydrate-derived or ethanol (EtOH)-derived calories (EDC)
Acsl4 fl/fl mice were obtained from Cyagen Biosciences (Jiangsu), and Fsp1 fl/fl mice and Ksp Cre-ERT2 mice were sourced from GemPharmatech (Jiangsu)
Blood sugar-friendly meals, consistent movement, and stress management remain foundational
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