The study, with its rigorous clinical design, confirmed that the intervention group exhibited significant improvements compared to the placebo group in menstrual cycle regularity (p=0.023), total testosterone levels (p=0.043), waist circumference (p=0.030), and quality of life (p=0.034), with no reported adverse effects ( Notably, the mechanisms of probiotics may involve modulation of gut microbiota composition, while prebiotics such as inulin-type fructans (ITF) can selectively promote the growth of beneficial bacteria like Bifidobacterium and Lactobacillus, enhancing SCFA production and subsequently improving gut barrier function, insulin sensitivity, and metabolic parameters ( 8 colony-forming unit (CFU)/g of Lactobacillus ( 6.3 Fecal microbiota transplantation FMT, an emerging microbial-based therapeutic strategy, involves the transfer of fecal microbial communities from healthy donors into the intestinal tract of patients to restore gut microbiota homeostasis ( Ruminococcus and Lactobacillus ( Lactobacillus and Clostridium to near-control levels, alongside a reduction in Prevotella
Han YH, Kim SH, Kim SZ, Park WH
2024;63(12):e202318783
We always recommend moving toward healthier eating more protein, fewer processed foods, better meal timing
however, it is not beneficial in women with low estrogen levels due to impaired ovarian function, such as those with premature menopause or problems with the HPO axis
Multiple delivery approaches have been developed to effectively improve intracellular delivery and the in vivo bioavailability of NADs
