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Lee, S.-C

Although the antiglycation activity of amlodipine was demonstrated in a kinetically established glycation model, only one drug concentration was tested, and the half-maximal inhibitory concentration (IC50) could not be determined

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Many related agents have played a role in preclinical animal experiments but rarely can be converted into clinical applications

Ten-to-twelve-month-old beagle dogs weighing between 9.8 and 12.8 kg were purchased from YaDong Experimental Animal Research Centre, Nanjing, China