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Side Effects Are Common, But Patterned The most common real-world adverse effects of GLP-1 therapy tend to be gastrointestinal: Nausea Vomiting Constipation Diarrhea Reflux or fullness Early satiety that feels excessive That does not make the class unsafe by default

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Monitoring for liver function, cholesterol, and white blood cell count is part of safe use protocol

However, in diabetic cardiomyopathy, there is a disruption in the quality control of mitochondria, which results in an inadequate fusion process, increased fission, and fragmentation [69]

Additionally, some people worry about becoming dependent on these medications or want more control over their treatment plan

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