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J Immunol 1999

"Heptapeptide semax attenuates the effects of chronic unpredictable stress in rats"

So the upside is higher

Bacteria that produce butyric acid can be used to treat IBD because of its anti-inflammatory activity

Discovered in 1905 in red meat, it was synthesized in the laboratory as early as 1927, but its precise physiological role was only elucidated in the second half of the 20th e century