These cells secrete a plethora of inflammatory mediators and cytokines, including interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor- (TNF-), and chemokines, which can recruit more immune cells to the lungs, perpetuating the inflammatory process and contributing to airway remodeling and lung tissue destruction
Dhitavat S, Ortiz D, Rogers E, Rivera E, Shea TB
& Mascareas, J
10.1080/13510002.2020.1787662 201 MurphyM
Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial
The presence of stabilizers like trehalose can enhance stability by protecting the peptides structure during lyophilization and storage