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Circulation 2022;145:e876-e94
It was the first drug officially approved for weight loss and paved the way for newer options
In the UK, NICE recommends GLP-1 receptor agonists for type 2 diabetes under specific circumstances, typically when metformin and other treatments have not achieved glycaemic targets, or in people with specific cardiovascular risk factors
It is formed from glass or medical-grade plastic
Long-term outcomes depend on treatment adherence and lifestyle integration
Brief room-temperature exposure for a few hours typically does not permanently damage semaglutide, but repeated or prolonged exposure degrades the active ingredient
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