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A prospective cohort study reported that combining sTfR and ferritin into a ratio-based index achieved an area under the curve (AUC) of 0.87 in predicting A-positivity, outperforming traditional individual biomarkers (Du et al., 2024)

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Researchers became interested because early studies showed that combining these peptides produced accelerated healing timelines and improved tissue quality outcomes compared to individual peptide applications