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These patients also exhibit deficits in auditory sensory processing that manifests as impaired mismatch negativity (MMN), which is an auditory evoked potential (AEP) component related to NMDA receptor function

42 It has now been established that some IL-6 effects are reliant on HO-1 activity as HO-1 has a central mechanistic action in the regulation of the complex antioxidant system and is a key node in multiple signaling pathways, including IL-6/Jak/STAT3

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