Which is why I love this story
Frequency of Administration: Initial Phase: 2-3 injections per week for the first month or two
This broadens access for patients who previously had no approved treatment options
Moreover, 6 week exposure to CUMS showed further GABA level reductions in tissues such as hippocampus, blood and feces, suggesting that more widespread neurotransmitter depletion may be stress type and duration dependant (Jia et al., 2024)
HMGB1 is a ubiquitously expressed nuclear protein engaged in the progression of nucleosome stabilization and DNA binding
Of note, she previously had gastroesophageal reflux disease, but these symptoms had resolved since she started tirzepatide (Mounjaro, Eli Lilly, Indianapolis, IN) 12.5 mg/0.5 mL pen injector injection (last dose 2 days before surgery)