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Circulation 116 , 21912202 (2007)

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However, these compounds are large molecules liraglutide (~3700 g/mol) and semaglutide (~4100 g/mol) and drugs of this size typically do not cross the placenta unless active transport mechanisms exist

2 Although strategies such as refined diagnostic criteria can improve case detection, large-scale database studies cannot match the diagnostic precision achieved through manual chart review, which remains the most reliable method for confirming NAION cases, the commentary authors wrote

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