Wegovy mimics the effects of GLP-1, reducing hunger and cravings by targeting receptors in the gut and brain
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In murine models of inflammatory arthritis, liraglutide treatment significantly reduced synovial inflammation, joint damage, and the expression of cytokines such as TNF- and IL-1, likely mediated through GLP-1R expressed on macrophages and fibroblast-like synoviocytes within the inflamed joint microenvironment [368,369,370]
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