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5,6 In multidrug-resistant HL60/VCR acute myelogenous leukemia cells, GST is found to be expressed at higher levels than HL60
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Recent studies have demonstrated that targeting deubiquitinases can effectively reduce the post-translational levels of NRF2 and YAP proteins, thereby decreasing the growth and chemoresistance of pancreatic cancer cells [124]
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For example, in pea plants susceptible to Plum pox virus (PPV), systemic PPV infection produced chlorotic and necrotic lesions, a pronounced oxidative stress indicated by increased protein oxidation, lipid peroxidation, elevated H 2 O 2 levels and electrolyte leakage in infected leaves (Daz-Vivancos et al., Rice black-streaked dwarf virus (RBSDV) displayed an induction of GST23 and the corresponding transcripts, concomitant with oxidative stress (Xu et al., 2013)
