In conclusion, the appearance of a metastatic lingual melanoma is a very rare event, hence close collaboration among different specialists is very important in case of suspicious pigmented lesions to ensure their early detection and a prompt treatment of such aggressive neoplasm
Alhadeff AL, Mergler BD, Zimmer DJ, Turner CA, Reiner DJ, Schmidt HD, Grill HJ, and Hayes MR
Under pathological conditions, the double injury of increased MG production and decreased MG degradation in renal tissues leads to the accumulation of this toxic metabolite, which may further exacerbate renal injury
Since folate is necessary for the synthesis of glutathione, an impaired ability to detoxify NAPQI is expected in these children
Our results suggest that epitalon has a positive effect on hTERT expression and telomerase activity in normal cells (IBR3 and HMEC), whereas in cancer cells (BT474 and 21NT), hTERT is elevated however, telomerase activity is not significantly enhanced
& Handa, J