& Liang, Y.-S
Antioxidants like glutathione are endogenous substances (substances naturally produced by your body) that take free radicals to task
An animal study showed that NAC increased histamine release in conjunction with fluoride.[ref] In people given IV n-acetylcysteine in a hospital setting for acetaminophen poisoning, about 8% of the patients had an anaphylactoid reaction, defined as cutaneous (urticaria, pruritus, angioedema) or systemic (hypotension, respiratory symptoms) within five hours of receiving the IV
M., & Aggarwal, B
It is also believed to be able to treat patients with hearing loss, specifically noise-related hearing loss, and hearing-loss due to ototoxicity
Due to its wide distribution in the cochlea, preferentially in the SV and the spiral ligament (Yamasoba et al., 1998), therapeutic strategies aimed at increasing glutathione levels have been used as a proof of principle for the treatment of NIHL in rodent models