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10.3390/antiox13080923

545 For example, pelacarsen, an Lp(a) ASO drug developed by Ionis in collaboration with Novartis AG, effectively lowers Lp(a) levels by selectively cleaving Apo(a) gene (LPA) mRNA

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While S in soluble proteins is estimated to be 6 to 10 times greater than the glutathione pool in optimal conditions (Queval et al., 2009), the difference can be shifted in oxidative stress conditions