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This conversion is ATP-dependent, requiring sufficient cellular energy to proceed at a normal rate

If antioxidant levels go down and oxidants increase, then oxidative stress occurs

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A high reading doesnt always indicate a problem, but it does have clinical significance depending on context

Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat

[ Treatment of human umbilical vein endothelial cells (HUVECs) with UA triggered inflammatory response mediated by significant elevation of expression levels of IL-1, IL-6 and ICAM