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The study follows speculation that the reduction in nutrient and water absorption by the body could have long-term health implications

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Ketogenesis occurs predominantly within the hepatic mitochondria, with carnitine palmitoyl transferase I (CPT-1) acting as the critical rate-limiting enzyme for mitochondrial fatty acid import (Figure 1)

Moreover, immunofluorescence assays showed that SP decreased the mean fluorescence intensity of KEAP1, whereas it increased the co-localization of KEAP1 and ubiquitin dose-dependently (Fig