tirzepatide and semaglutide tablets vs Trial Results Why Tirzepatide/Semaglutide tablets? 💊✨No needles

Why do we compare trials of different durations and populations

The downstream effects include: Synaptogenesis : Formation of new synaptic connections in hippocampal neurons, driven by c-Met-mediated activation of PI3K/AKT and MAPK/ERK signaling cascades Spinogenesis : Growth of new dendritic spines, the structural substrate for excitatory synaptic transmission Neurotrophic support : In cell-based neurotrophic assays, Dihexa demonstrated potency approximately seven orders of magnitude greater than BDNF The HGF/c-Met pathway is distinct from the BDNF/TrkB and NGF/TrkA pathways targeted by most nootropic peptides

Apart from side effects which seem to be minor, mainly involving nausea there are a few other downsides of semaglutide

So, this is a prescription pair

doi:10.1016/S0140-6736(19)31149-3 16Marso SP, Bain SC, Consoli A, et al

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