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However, after the SELECT trial showed 20% MACE reduction, CMS issued guidance in March 2024 allowing Part D coverage of Wegovy specifically for cardiovascular risk reduction in patients with established CVD and a BMI of 27 or higher

As previously described 14 with slight modification, DVT was induced by incomplete ligation of both infrarenal veins leading to partial stagnation of blood

A first-in-human, randomized, double-blind, placebo-controlled phase I study in healthy volunteers (clinical trial ID: NCT05027568) demonstrated that oral IOA-289 was well tolerated with no clinically significant adverse events

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