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There have been no further randomized control trials to evaluate the efficacy of POTABA

2006 Sep;114(9):1438-44

0.72 for liraglutide

Increased risk of vertebral fracture in patients with diabetes: A meta-analysis of cohort studies

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Bottom Line on Effectiveness: For Maximum Weight Loss: Tirzepatide produces better results on average (7.6% more body weight lost) For Proven Long-Term Safety: Semaglutide has been on the market longer with more real-world data For Best Value: Compounded semaglutide at $199/month provides excellent results at lowest cost For Most People: Both medications are highly effective