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Numerous etiologic factors have been proposed, including physiologic factors, reactive factors, developmental factors, racial factors, Peutz-Jeghers syndrome, environmental stress, exposure to sunlight, trauma, smoking, medications such as antimalarial agents, hemochromatosis, systemic conditions such as Addisons disease and other endocrine disturbances, chronic pulmonary disease, and idiopathy

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Wegovy was approved in the US in 2021 and did not reach Australia until 2023

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GIPR-Camper neurons of the AP were excited using a light-emitting diode (LED) light source (Dual Optoled, Cairn Research) at 435 nm for 50 ms every 3 s, and CFP and YFP emissions were simultaneously recorded after passing through an optosplit (Cairn Research