Tirzepatide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes
The authors highlight three urgent priorities: Reframing GLP1 receptor agonists as essential medicines to reduce multimorbidity and premature mortality Addressing inequitable access and affordability, particularly in low and middleincome countries Strengthening healthsystem capacity, alongside prevention and behavioural support, to deliver safe and effective obesity care As the paper makes clear, prevention and treatment are codependent, stigma remains a major barrier, and lessons from HIV show what is possible when access, advocacy and systems change move together.
PMC 12026077
12 Another study found that even bariatric surgery is more cost-effective
Athauda D, Maclagan K, Skene SS, Bajwa-Joseph M, Letchford D, Chowdhury K, et al
Rapid weight loss, a primary effect of the medication, can alter biomechanics and joint loading patterns, potentially causing musculoskeletal discomfort during the adaptation period