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This plays a role in its many functions

Once activated, they upregulate antigen-presentation and costimulatory pathways, thereby re-stimulating myelin-reactive T cells within the CNS and sustaining the adaptive response

10.1007/s12035-020-02277-7 167 ZhangH.GuoJ.ChuJ.YuH.ZhangJ.MaS.et al (2025)

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Burning and dryness are also possible, albeit uncommon reactions