Khan MA, et al
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Point mutations or deletions of the -globin gene cluster, which is located on the human chromosome 11 p15.3 locus, induce -thal pathogenicity by reducing or eliminating -globin synthesis (Taher et al., 2018)
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Asia Pacific Cohort Studies Collaboration
Its job is specific: it inhibits an enzyme called NNMT nicotinamide N-methyltransferase that becomes overactive in fat tissue, especially as we age