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TB500 improves tissue repair and cell movement by regulating actin, essential for cell shape and movement

Several studies have demonstrated potential HDAC inhibitors in treatment of SAM (Mohseni et al., 2013) Histone acetylation has been shown to upregulate SMA 2 expression (Kernochan et al., 2005)

Studies show the peptide increases dendritic spine density by 40-60% in treated brain regions, with formation of new functional synaptic connections confirmed by electrophysiological recordings demonstrating enhanced synaptic transmission and long-term potentiation

Tissue inhibitors of metalloproteinases (TIMPs) increase across all concentrations tested

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Three reasons: (1) reported lifespan extension and reduced spontaneous tumour incidence in chronically treated rodents