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Furthermore, calcinosis is a common complication of chronic jDM, leading to long-term disability and sometimes death (183, 188)

Add trypsin antigen retrieval solution and incubate at 37 C for 15 min

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62 reported that ERS was observed in mice 12 h after APAP treatment, and APAP evidently induced liver injury by activating CHOP

The NLRP3 inflammasome is activated by lipid peroxidation byproducts such as 4-HNE and MDA produced during ferroptosis, triggering caspase-1-dependent maturation of IL-1/IL-18, which amplifies inflammation and establishes a vicious cycle (127, 131)

For example, anti-epileptic drugs (AEDs) change the chemicals in the brain to stop seizures, but they do not cure epilepsy