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The production of PUFAs requires the activation of the ACSL4-LPCAT3 (acyl-CoA synthetase long-chain family member 4-lysophosphatidylcholine acyltransferase 3) pathway

These are precisely the cytokines elevated in the peritoneal fluid of endometriosis patients

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found that using 3,3-diindolyl methane or indole-3-carbinol to inhibit FMO3 could be a suitable target to control TMAO production (147)

The practical outcome is straightforward

If you are post-thyroidectomy and considering tirzepatide, ensure your endocrinologist is aware and has planned a monitoring schedule before you start treatment