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Proton pump inhibitors (PPIs) and H2-receptor antagonists, used for acid reflux, reduce stomach acid production, which can impair dietary B12 absorption, though this does not directly affect injections

Genetic Factors: Some individuals have MTHFR gene mutations, making it incredibly difficult to process synthetic B12

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These methods typically yield short-term results followed by aggressive weight regain

Following, the complex enters the nucleus, where it binds to another transcriptional factor and to the DNA producing induction and gene rebuke, what finally leads to its anti-inflammatory, immunosuppressant and mineral corticoid effect

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