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Regulatory bodies like the FDA and EMA impose stringent guidelines for clinical trials, requiring extensive safety and efficacy data

The analgesic activity of paracetamol is prevented by the blockade of cannabinoid CB1 receptors

Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology

In humans with parkin mutations, mitochondrial complex I activity is impaired (Mftoglu et al., 2004)

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Cell culture Swiss 3T3 fibroblasts, obtained from American Type Culture Collection (ATCC CCL 92), were maintained at 37 in Dulbecco's modified Eagle's medium supplemented with 25 mM HEPES (pH 7.4), 10% (v/v) fetal bovine serum, 100 units/mL penicillin, and 100 mg/mL streptomycin