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Cell culture Clonal insulin-secreting BRIN-BD11 cells were maintained in RPMI 1640 medium containing 11.1 mM glucose, supplemented with 10% foetal bovine serum (FBS), 100 U/ml penicillin and 0.1 mg/ml streptomycin, pH 7.4, as described previously 45

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However, the market faces challenges, including high medication costs compared to traditional diabetes treatments, insurance coverage limitations for premium therapies, and supply constraints for specialized manufacturing

Conservative estimates for the medical costs associated with overweightness and obesity in China have been projected to 61 billion USD