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Various biologics mainly include anti-TNF- monoclonal antibody(mAb), anti-47 mAb, IL-12/23 mAb, and JAK inhibitor, and they have been approved for moderate to severe UC, showing greater success than conventional treatments like 5-ASA and corticosteroids [163] (Table 1)

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Experience measurable oxidative degradation at temperatures above 15C, with methionine losing 1218% potency within 72 hours at 25C

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