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Comparing Semaglutide to Tirzepatide for Abdominal Fat Loss Tirzepatide (a GLP-1/GIP dual agonist) shows slightly faster visceral fat reduction than semaglutide alone in head-to-head studies because it activates two appetite-control pathways instead of one

Both medications help regulate appetite and metabolism, so discontinuing treatment should be done under medical supervision to ensure you have a plan for maintaining weight loss

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Low blood sugar can occur, especially if taking medication for diabetes