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Regular follow-up with primary care providers ensures comprehensive management of these interconnected conditions, optimizing both liver and overall health outcomes

For example, delayed gastric emptying can cause both nausea and constipation simultaneously, while rapid intestinal transit may produce diarrhea

Excessive Fe 2+ can react with lipid radicals and H 2 O 2 to produce a large amount of reactive oxygen species (ROS), which can damage membrane lipids, proteins, DNA, and other biological macromolecules, causing ferroptosis (22)

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Monitor closely for adverse events such as respiratory depression, sedation, and hypotension [see Clinical Pharmacology (12.3)]