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If its too warm, the protein in the medication can break down

Melatonin Melatonin has shown promise as a treatment for CIPN based on animal studies (Galley 2017

CIPN, chemotherapy-induced peripheral neuropathy

You have to be very careful with graves because the patient can have a thyroid storm and end up in the emergency room

Although oral dosing may be a more appealing option versus parenteral administration for many patients and prescribing physicians [1216], mAbs are not amenable to oral dosing because they are prone to proteolysis and denaturation by gastrointestinal (GI) enzymes and generally have limited membrane permeability due to their large molecular weight (approximately 150 kDa) [1719]

That is not a political statement