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Preclinical studies with a long-acting polyethylene glycosylated (PEGylated) FGF21 analog, B1344, in non-human primates with non-alcoholic liver disease demonstrated reduction of steatosis, attenuation of inflammation and fibrosis, and reduced hepatocyte injury after 11 weeks of therapy as assessed by analyzing liver biopsies [36]
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The main perioperative concern is pulmonary aspiration during general anaesthesia when protective airway reflexes are suppressed
Weight Loss Surgery Is Not The Easy Way OutIt Is a Powerful Metabolic Tool Modern bariatric surgery works by changing hunger, fullness, portion tolerance, gut hormones, and metabolic signaling
GLP-1 receptor agonists mimic a naturally occurring gut hormone called glucagon-like peptide-1 (GLP-1), which slows how quickly food moves from your stomach into your small intestine
Scheper W, Hoozemans JJ
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