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Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial

Some people lose muscle mass if they do not combine treatment with strength training and adequate protein

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Safety depends on proper manufacturing, accurate dosing, and provider monitoring

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To manage post-meal diarrhea: Eat 50% smaller portions than usual to reduce the digestive burden Wait 30 minutes after eating before engaging in physical activity Eat slowly and chew food thoroughly to aid digestion Keep a food diary to identify specific triggers that may worsen symptoms Most patients find that post-meal diarrhea improves significantly by week 4 of treatment as the body adjusts to the medication