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The virus rapidly generates intracellular free radicals and actively inhibits the DNA damage repair proteins necessary for the body to synthesize its own glutathione

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As an experimental system we used a human BBB co-culture model improved by cARLA

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White and Granick, 1963) and genomic studies ( hemH ), allowing it to catalyse the insertion of iron into PPIX (Schlr et al., 2000)