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Wegovy is also approved for use in children and adolescents 12 years of age or older with obesity

GLP-1RA, as a glucose reducing medication, can reduce the glycation process and the production of AGEs

Literature data confirm these findings, showing that GLP1RA improved the redox state and mitochondrial respiration of leukocytes, and diminished leukocyte-endothelial interactions, inflammation, and carotid intima-media thickness 75

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Understanding the redox regulation may have important clinical ramifications in understanding the pathogenesis of liver diseases and developing therapeutic approaches