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10 In conclusion, the multidistrict action of GLP1RA and SGLT2i provide a unique opportunity to simultaneously address multiple pathological pathways driving PAD progression ( Figure 1 )
One study showed the success rate of such a regimen is 80%, which is comparable to the success rate of donor-matched bone marrow transplantation (Jaing 2012)
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When to contact your healthcare provider Contact your healthcare provider right away if you have: Thoughts of suicide or self-harm Severe rash, skin peeling, or blisters Yellowing of your skin or eyes Dark urine or upper stomach pain Confusion, rapid heart rate, or severe muscle stiffness Unusual or heavy bleeding Signs of a severe allergic reaction, like swelling of the face, lips, or throat, or trouble breathing References Cymbalta (duloxetine) prescribing information
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