1d), suggesting that endogenous MOTS-c is largely depleted by aging
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Patients on lisinopril, metoprolol, hydrochlorothiazide, and amlodipine have been successfully treated with GLP-1 therapy in clinical practice without major safety signals
Circumstances where stopping may be appropriate include intolerable side effects (such as persistent nausea or gastrointestinal symptoms), pregnancy or planning pregnancy, development of contraindications, or achievement of diabetes remission through significant lifestyle changes
There are two - both of which are currently available in the US
Strober B, Blauvelt A, Warren RB, Papp KA, Armstrong AW, Gordon KB, Morita A, Alexis AF, Lebwohl M, Foley P, Kisa RM, Colston E, Wang T, Banerjee S, Thaci D (2024) Deucravacitinib in moderate-to-severe plaque psoriasis: pooled safety and tolerability over 52 weeks from two phase 3 trials (POETYK PSO-1 and PSO-2)
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