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Gut-derived metabolites (e.g., SCFAs, indoles, secondary bile acids) and oxylipin signatures converge on metabolic pathways central to the CITleucineexercise synergy

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During the conduct of general anaesthesia/deep sedation, children on GLP-1 agonists have similar gastrointestinal adverse events at a rate similar to adults

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And they hit your gastrointestinal system hard if you start at a full therapeutic dose without giving your body time to adapt

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